There are many things which can affect how the insulin is absorbed from the injection site into the bloodstream. It includes:
Mode of administration
Selecting the 'right' dose and timing
Selecting a suitable insulin preparation (typically on 'speed of onset and duration of action' grounds)
Adjusting dosage and timing to fit food intake timing, amounts, and types
Adjusting dosage and timing in accordance with exercise undertaken
Adjusting dosage, type and timing according to other conditions like stress, illness etc
The dosage is non-physiological in that a subcutaneous bolus dose of insulin alone is administered instead of combination of insulin
It is dangerous in case of mistake (Hypoglycemia or Hyperglycemia)
Once open insulin may be preserved for 30 days at temperature less than 86 °F.
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